profender cats side effects
Most cats hate to be held firmly and forced to ingest a medication. Turn the cap over and place the other end of cap onto the tip of the tube. Available for Android and iOS devices. In rare cases, the drug can trigger vomiting and diarrhea. In rare cases, the drug can trigger vomiting and diarrhoea. All rights reserved. Emodepside, a semi-synthetic molecule, is a cyclic depsipeptide. Pregnant women, or women who may become pregnant, should avoid direct contact with, or wear disposable gloves when applying, this product. Select the package that correctly corresponds with the body weight of the cat. To ensure the entire contents of the tube are administered, place the tip of the tube on the skin and squeeze the entire contents directly onto the skin. In yet other cases, you may see a cat with shaking and tremors because of this drug. He studied creative writing at Mankato State University in Minnesota. Every effort has been made to ensure the accuracy of the Profender (emodepside/praziquantel) Topical Solution information published above. Quinoline derivatives and related substances [5]. Safety Study in Heartworm Positive Cats: Cats artificially infected with adult heartworms harvested from dogs were treated topically with PROFENDER Topical Solution at 0X, 1X or 5X the recommended dose once a month for three treatments. Part the hair on the back of the cat’s neck at the base of the head, until the skin is visible. Clinical signs included salivation (one 1X and three 5X cats), labored breathing (all groups) and lethargy (one 5X cat). (See ANIMAL SAFETY.). Your email address will not be published. In general, the scratching is not a big concern. One cat treated with a vehicle placebo (formulation minus the active ingredients) showed salivation, gagging, lethargy and a swollen tongue. He speaks fluent Mandarin Chinese, English and reads Spanish. provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. People with known hypersensitivity to butylhydroxyanisole, emodepside or praziquantel should administer the product with caution. For customer service or to obtain product information, including the MSDS, call 1-800-633-3796. Regulations for product use are established by country. Adverse reactions reported by the cat owners included licking/ excessive grooming in 18 cats (3.0%), scratching treatment site in 15 cats (2.5%), salivation in 10 cats (1.7%), lethargy in 10 cats (1.7%), alopecia in 8 cats (1.3%), agitation/nervousness in 7 cats (1.2%), vomiting in 6 cats (1.0%), diarrhea in 3 cats (0.5%), eye irritation in 3 cats (0.5%), respiratory irritation in 1 cat (0.2%) and shaking/tremors in 1 … Select one or more newsletters to continue. In a total of 13 controlled laboratory studies to establish effectiveness, 149 cats were treated with PROFENDER Topical Solution. The normally prescribed minimum dosage is 0.063 ml/lb (0.14 ml/kg) of Profender, equivalent to a combination of 5.45 mg/lb praziquantel and 1.36 mg/lb emodepside, applied topically [3, 10]. © 2020 ( The physical side effects of Profender include hair loss and excessive salivation. Subscribe to newsletters for the latest medication news, alerts, new drug approvals and more. General Safety Study in Kittens: PROFENDER Topical Solution was topically applied at 0X (vehicle control), 1X, 3X and 5X the maximum dose to 48 healthy 8-week-old kittens every two weeks for six doses. Of those, 606 received a single treatment with PROFENDER Topical Solution. The cats enrolled in the field study were heartworm antigen and antibody negative prior to entering the study. PROFENDER Topical Solution is indicated for the treatment and control of hookworm infections caused by Ancylostoma tubaeforme (adults, immature adults, and fourth stage larvae), roundworm infections caused by Toxocara cati (adults and fourth stage larvae), and tapeworm infections caused by Dipylidium caninum (adults) and Taenia taeniaeformis (adults) in cats. A few behavioural side effects can occur after Profender is applied. As a spot-on topical solution, it may be prescribed for treating infections caused by the different stages of canine roundworm, hookworm, lungworm, as well as adult tapeworms in cats [3]. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or online at 4. He has been writing since 1987 and has written for NPR, AP, Boeing, Ford New Holland, Microsoft, RAHCO International, Umax Data Systems and other manufacturers in Taiwan. Oral exposure can cause salivation and vomiting. Using the Profender topical solution may cause a few adverse reactions in cats, including scratching the application site, too much licking, lethargy, drooling or foaming at the mouth, loss of hair, vomiting, diarrhea, respiratory and eye irritation, tremors, and nervousness [6, 9]. There the two active ingredients interact with the systems of the susceptible parasites [1]. May be harmful if swallowed. All of the physical side effects are a direct result of the cat ingesting the drug, a label contraindication. 3. Box 390, Shawnee Mission, Kansas 66201 U.S.A. The cats exhibited salivation, vomiting, tremors, abnormal gait, abnormal respiration and weight loss. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Avoid contact with the application area while it is wet and wash hands thoroughly with soap and warm water after handling. Vet Info: An Introduction to Profender for Cats, Pet Place: Emodepside/Praziquantel (Profender), Profender Topical Solution Side Effects. 82482521/03615026/82482572/03615034/82482580/82482602, R.2. One 5X kitten experienced salivation and tremors and another 5X kitten experienced salivation on the day of dosing. Oral Safety Studies in Cats: PROFENDER Topical Solution was administered orally at the recommended topical dose to young adult cats. Profender is a topical medication to help treat several common cat worms. Updated: 2020-09-29. Avoid its use on broken skin or wet coat [3], and make sure not to get the medicine in your cat’s eyes or mouth [6]. If re-infection occurs, the product can be re-applied after 30 days. Three cats vomited within 24 hours of dosing, one each in vehicle control, 3X and 5X groups. In rare cases, the drug can trigger vomiting and diarrhoea. Less than 8 weeks old or weigh less than 2.2lbs, Hypersensitive to its primary ingredients, Profender® Topical Solution (emodepside/praziquantel) –, Profender (emodepside/praziquantel) Topical Solution –, Diagnosis and Management Of Lungworm Infections in Cats –, Emodepside/Praziquantel (Profender®) for Dogs and Cats –, Profender Topical Parasiticide for Small Cats (Canada) –. In yet other cases, you may see a cat with shaking and tremors because of this drug. Treatment at the base of the head will minimize the opportunity for ingestion while grooming. 7. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 30 Sep 2020) and others. Post-Approval Experience: The following adverse events are based-on post-approval adverse drug experience reporting. The effectiveness of this product when used before bathing has not been evaluated. * Cats over 17.6 lbs should be treated with the appropriate combination of tubes. Profender should not be used in young animals (cats under 8 weeks of age or weighing less than 0.5 kg, or puppies under 12 weeks of age or weighing less than 1 kg). Praziquantel is an isoquinoline cestocide. A few behavioural side effects can occur after Profender is applied. While the use of the drug did not appear to be the direct cause of death, treatment with the drug cannot be ruled out as a contributing factor (See PRECAUTIONS). The physical side effects of Profender include hair loss and excessive salivation. To report suspected adverse events and/or to obtain a copy of the MSDS or for technical assistance, call Bayer Animal Health at 1-800-633-3796. In some cases, you may notice eye and respiratory irritation. In the field study conducted at 13 veterinary clinics/hospitals, 837 purebred or crossbred cats from single and multi-cat households were enrolled to evaluate safety and effectiveness under field conditions of use.


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